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Hydrogen gas inhalation after myocardial infarction

In Cardiovascular, Human studies by CHESS

Hydrogen gas inhalation (HI) reduced infarct size and mitigated adverse left ventricular (LV) remodeling in a rat model of acute myocardial infarction (AMI). The authors designed a prospective, open-label, rater-blinded clinical pilot study in patients experiencing ST-elevated MI (STEMI). The 20 patients with an initial diagnosis of STEMI were assigned to either an HI group (1.3% H2with 26% oxygen) or …

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Cardioprotective effect of hydrogen-rich saline on myocardial infarction

In Animal studies, Cardiovascular by CHESS

Infusion with hydrogen gas-saturated saline has recently been reported to exert antioxidant and anti-inflammatory activity that may protect against organ damage induced by oxidative stress. Therefore because oxidative stress plays a significant role in the pathophysiology of myocardial infarction (MI), the aim of this study was to investigate whether hydrogen-rich saline has cardioprotective effects against isoproterenol-induced MI in rats. An …

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Hydrogen gas reduces infarct size in the rat model of myocardial ischemia

In Animal studies, Cardiovascular by CHESS

Inhalation of hydrogen (H(2)) gas has been demonstrated to limit the infarct volume of brain and liver by reducing ischemia-reperfusion injury in rodents. When translated into clinical practice, this therapy must be most frequently applied in the treatment of patients with acute myocardial infarction, since angioplastic recanalization of infarct-related occluded coronary artery is routinely performed. Therefore, we investigate whether H(2) …