Hydrogen inhalation was neuroprotective in several brain injury models. Its mechanisms are believed to be related to antioxidative stress. Authors investigated the potential neurovascular protective effect of hydrogen inhalation especially effect on mast cell activation in a mouse model of intracerebral hemorrhage in controlled in vivo laboratory study in one hundred seventy-one 8-week-old male CD-1 mice. Collagenase-induced intracerebral hemorrhage model …