Exploring Hydrogen

C enter for Health, Exercise and Sport Sciences (CHESS) is an educational and research institution focused to advance human health through multidisciplinary science, comprehensive education and public outreach. Using basic science, clinical, behavioral and community-based research approaches, we strive to develop novel therapeutic strategies that promote health and quality of life in both athletic and clinical environment. Molecular hydrogen might be one of them!

Our H2 research focuses to 4 areas: exercise performance, cardiometabolic disorders, neurodegeneration, and musculoskeletal injury, with relevant studies registered at ClinicalTrials.gov, a resource run by the US National Library of Medicine at the National Institutes of Health. In 2010, our team started the first study evaluating the effects of hydrogen-rich water on biomarkers of fatigue in physically actives. We recently evaluated the effects of molecular hydrogen-releasing minerals on metabolic fitness in middle age overweight women. Our group just completed a trial how short-term hydrogen inhalation affects cognitive performance in elderly aged 65 and above. In addition, we assessed the impact of oral and topical hydrogen on sport-related injuries of the muscles, tendons and ligaments in male athletes.

The Prinicipal Investigator

Sergej M. Ostojic

Prof. Sergej M. Ostojic, MD, PhD

Sergej M. Ostojic is a Professor of Biomedical Sciences at the University of Novi Sad, and Adjunct Professor at the University of Belgrade School of Medicine. He currently researches how different mitochondria-targeted interventions tackle impaired bioenergetics in health and disease, and has authored over 250 peer-reviewed articles in top-tier journals including The Lancet, Nature, BMJ, Theranostics, Mayo Clinic Proceedings, Clinical Science, Pharmacological Research, European Journal of Nutrition etc. He is a member of the American Society for Nutrition, the American Physiological Society, the International Society for Cerebral Blood Flow and Metabolism, and the Nutrition Society.

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Papers on Pubmed

Our Research in Numbers

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Co-Investigators from

University of Novi Sad
University of Basque Country
University of Central Florida
Universidad de Granada
University of Belgrade


Center for Health, Exercise and Sport Sciences
STARI DIF, Deligradska 27, Belgrade 11000, Serbia
+381 68 5226115


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