View Post

Breathing hydrogen-oxygen mixture decreases inspiratory effort

In Cardiovascular, Human studies by CHESS

Hydrogen-oxygen mixture (H2-O2) may reduce airway resistance in patients with acute severe tracheal stenosis, yet data supporting the clinical use of H2-O2 are insufficient. The authors evaluated the efficacy and safety of breathing H2-O2 in acute severe tracheal stenosis. Thirty-five consecutive patients with severe acute tracheal stenosis were recruited in this prospective self-control study. Air, H2-O2 and O2 inhalation was …

View Post

Inhalation of hydrogen in Parkinson’s disease

In Human studies, Nervous system by CHESS

Hyposmia is one of the earliest and the most common symptoms in Parkinson’s disease (PD). The benefits of hydrogen water on motor deficits have been reported in animal PD models and PD patients, but the effects of hydrogen gas on PD patients have not been studied. The authors evaluated the effect of inhalation of hydrogen gas on olfactory function, non-motor …

View Post

Hydrogen-controlled cancer

In Cancer, Human studies by CHESS

Advanced cancer treatment is a huge challenge and new ideas and strategies are required. Hydrogen exerts antioxidant and anti-inflammatory effects that may be exploited to control cancer, the occurrence and progression of which is closely related to peroxidation and inflammation. The authors conducted a prospective follow-up study of 82 patients with stage III and IV cancer treated with hydrogen inhalation …

View Post

Hydrogen-rich water affects antioxidant activity and gut flora in soccer players

In Exercise, Human studies by CHESS

Expending a considerable amount of physical energy inevitably leads to fatigue during both training and competition in football. An increasing number of experimental findings have confirmed the relationship between the generation and clearance of free radicals, fatigue, and exercise injury. Recently, hydrogen was identified as a new selective antioxidant with potential beneficial applications in sports. The present study evaluated the …

View Post

Hydrogen gas inhalation after myocardial infarction

In Cardiovascular, Human studies by CHESS

Hydrogen gas inhalation (HI) reduced infarct size and mitigated adverse left ventricular (LV) remodeling in a rat model of acute myocardial infarction (AMI). The authors designed a prospective, open-label, rater-blinded clinical pilot study in patients experiencing ST-elevated MI (STEMI). The 20 patients with an initial diagnosis of STEMI were assigned to either an HI group (1.3% H2with 26% oxygen) or …

View Post

Efficacy of inhaled hydrogen on neurological outcomes following brain ischemia during post-cardiac arrest

In Human studies, Nervous system by CHESS

Hydrogen gas inhalation (HI) improved survival and neurological outcomes in an animal model of post-cardiac arrest syndrome (PCAS). The feasibility and safety of HI for patients with PCAS was confirmed in a pilot study. The objective of this study is to evaluate the efficacy of HI for patients with PCAS. The efficacy of inhaled HYdrogen on neurological outcome following BRain …

View Post

Hydrogen gas inhalation in acute cerebral infarction

In Human studies, Nervous system by CHESS

Molecular hydrogen (H2) acts as a therapeutic antioxidant. Inhalation of H2 gas (1-4%) was effective for the improvement of cerebral infarction in multiple animal experiments. Thus, for actual applications, a randomized controlled clinical study is desired to evaluate the effects of inhalation of H2 gas. Here, the authors evaluate the H2 treatment on acute cerebral infarction. Through this randomized controlled …

View Post

Effects of hydrogen rich water on prolonged intermittent exercise

In Exercise, Human studies by CHESS

Recent studies showed a positive effect of Hydrogen Rich Water (HRW) intake on acid-basic homeostasis at rest. The authors investigated 2-weeks of HRW intake on repeated sprint performance and acid-base status during prolonged intermittent cycling exercise. In a cross over single-blind protocol, eight trained male cyclists (age [mean ± SD] 41±7 years, body mass 72.3±4.4 kg, height 1.77±0.04 m, maximal …

View Post

Hydrogen-rich water positively affects exercise capacity in mid-age overweight women

In Exercise, Human studies by CHESS

Molecular hydrogen (H2) improves body composition, metabolic profiles and mitochondrial function in overweight women, yet no studies so far evaluated the effectiveness of H2 for improving exercise capacity in this population. The authors examined the effects of 28-days supplementation with 1 L per day of hydrogen-rich water (HRW) on exercise capacity and quality of life in overweight mid-age women. Twelve …

View Post

Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with chemotherapy

In Cancer, Human studies by CHESS

The present study was conducted to investigate the protective effect of hydrogen-rich water on the liver function of colorectal cancer (CRC) patients treated with mFOLFOX6 chemotherapy. A controlled, randomized, single-blind clinical trial was designed. A total of 152 patients with CRC were recruited by the Department of Oncology of Taishan Hospital (Taian, China) between June 2010 and February 2016, among …