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Hydrogen-rich water for improvements of mood, anxiety, and autonomic nerve function in daily life

In Human studies, Nervous system by CHESS

Health and a vibrant life are sought by everyone. To improve quality of life (QOL), maintain a healthy state, and prevent various diseases, evaluations of the effects of potentially QOL-increasing factors are important. Chronic oxidative stress and inflammation cause deteriorations in central nervous system function, leading to low QOL. In healthy individuals, aging, job stress, and cognitive load over several …

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Molecular hydrogen positively affected post-exercise recovery

In Exercise, Human studies by CHESS

Molecular hydrogen (H2) recently appeared as a novel and safe ergogenic agent that might have beneficial effects in athletes. However, no information is available concerning the impact of H2 on post-exercise recovery indices. The purpose of this study was to determine the effects of pre-exercise H2 administration on post-exercise heart rate and blood lactate responses in judo athletes. Five athletes …

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Hydrogen gas for post-cardiac arrest syndrome

In Cardiovascular, Human studies by CHESS

Hydrogen gas inhalation (HI) ameliorates cerebral and cardiac dysfunction in animal models of post-cardiac arrest syndrome (PCAS). HI for human patients with PCAS has never been studied. Between January 2014 and January 2015, 21 of 107 patients with out-of-hospital cardiac arrest achieved spontaneous return of circulation. After excluding 16 patients with specific criteria, 5 patients underwent HI together with target …

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Improvement of psoriasis-associated arthritis by treatment with molecular hydrogen

In Human studies, Inflammation, Skin by CHESS

Psoriasis, a chronic inflammatory skin disease, is caused by infiltrating lymphocytes and associated cytokines, including tumor necrosis factor (TNF)α, interleukin (IL)-6, and IL-17. Effective treatments, including pathogenesis-based biological agents against psoriasis, are currently under development. Although the role of reactive oxygen species (ROS) in the pathogenesis of psoriasis has been investigated, it remains to be fully elucidated; ROS-targeted therapeutic strategies …

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Effectiveness of oral and topical hydrogen for sports-related soft tissue injuries

In Human studies, Muscle by CHESS

Because hydrogen therapy has been found beneficial for the treatment of inflammation, ischemia-reperfusion injury, and oxidative stress in humans, it seems useful to evaluate the effects of exogenously administered hydrogen as an element in the immediate management of sports-related soft tissue injuries. The main aim of this pilot study was to examine the effects of 2-week administration of hydrogen on …

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Hydrogen water intake via tube-feeding for patients with pressure ulcer

In Human studies, Skin by CHESS

Pressure ulcer (PU) is common in immobile elderly patients, and there are some research works to investigate a preventive and curative method, but not to find sufficient effectiveness. The aim of this study is to clarify the clinical effectiveness on wound healing in patients with PU by hydrogen-dissolved water (HW) intake via tube-feeding (TF). Furthermore, normal human dermal fibroblasts OUMS-36 …

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Breath hydrogen produced by ingestion of commercial hydrogen water

In Human studies, Metabolism by CHESS

This study compared how and to what extent ingestion of hydrogen water and milk increase breath hydrogen in adults. Five subjects without specific diseases, ingested distilled or hydrogen water and milk as a reference material that could increase breath hydrogen. Their end-alveolar breath hydrogen was measured. Ingestion of hydrogen water rapidly increased breath hydrogen to the maximal level of approximately …

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Hydrogen-rich water improved liver function in patients with chronic hepatitis B

In Human studies, Inflammation by CHESS

This study investigated effects of hydrogen-rich water (HRW) on oxidative stress, liver function and HBV DNA in patients with chronic hepatitis B (CHB). Sixty patients with CHB were randomly assigned into routine treatment group or hydrogen treatment group in which patients received routine treatment alone or additional oral HRW (1200-1800 mL/day, twice daily), respectively, for 6 consecutive weeks. Serum oxidative …

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Hydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function

In Metabolism by CHESS

Authors have found that hydrogen (dihydrogen; H2) has beneficial lipid-lowering effects in high-fat diet-fed Syrian golden hamsters. The objective of this study was to characterize the effects of H2-rich water (0.9-1.0 l/day) on the content, composition, and biological activities of serum lipoproteins on 20 patients with potential metabolic syndrome. Serum analysis showed that consumption of H2-rich water for 10 weeks …

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Molecular hydrogen inhalation in acute cerebral ischemia patients

In Human studies, Nervous system by CHESS

In animal experiments, use of molecular hydrogen (H2) has been regarded as quite safe and effective, showing benefits in multiple pathological conditions such as ischemia-reperfusion injury of the brain, heart, kidney and transplanted tissues, traumatic and surgical injury of the brain and spinal cord, inflammation of intestine and lung , degenerative striatonigral tissue and also in many other situations. However, …