View Post

Hydrogen rich water attenuates renal injury and fibrosis

In In vitro studies by CHESS

The current research was designed to study the role of hydrogen in renal fibrosis and the renal epithelial to mesenchymal transition (EMT) induced by transforming growth factor-β1 (TGF-β1). Hydrogen rich water (HW) was used to treat animal and cell models. Unilateral ureteral obstruction (UUO) was performed on Balb/c mice to create a model of renal fibrosis. Human kidney proximal tubular …

View Post

Preventive effects of drinking hydrogen-rich water on gingival oxidative stress and alveolar bone resorption

In Animal studies, Other studies by CHESS

Obesity induces gingival oxidative stress, which is involved in the progression of alveolar bone resorption. The antioxidant effect of hydrogen-rich water may attenuate gingival oxidative stress and prevent alveolar bone resorption in cases of obesity. The authors examined whether hydrogen-rich water could suppress gingival oxidative stress and alveolar bone resorption in obese rats fed a high-fat diet. Male Fischer 344 …

View Post

Hydrogen-rich water protects against inflammatory bowel disease

In Animal studies, Inflammation, Other studies by CHESS

The aim of this stuyd was to investigate the therapeutic effect of hydrogen-rich water (HRW) on inflammatory bowel disease (IBD) and to explore the potential mechanisms involved. Male mice were randomly divided into the following four groups: control group, in which the mice received equivalent volumes of normal saline (NS) intraperitoneally (ip); dextran sulfate sodium (DSS) group, in which the …

View Post

Hydrogen treatment protects against cell death and senescence induced by oxidative damage

In In vitro studies by CHESS

Hydrogen has potential for preventive and therapeutic applications as an antioxidant. However, micro- and macroparticles of hydrogen in water disappear easily over time. In order to eliminate reactive oxygen species (ROS) related with the aging process, the authors used functional water containing nanoparticle hydrogen. Nanoparticle hydrogen does not disappear easily and collapse under water after long periods of time. They …

View Post

Effect of hydrogen-rich water on the CD34 expression in brain tissue of rats with brain injury

In Animal studies, Nervous system by CHESS

The main aim of this study was to observe the effect of hydrogen-rich water on the CD34 expression and angiogenesis in lesion boundary brain tissue of rats with traumatic brain injury (TBI). A total of 54 adult male Sprague-Dawley (SD) rats were divided into three groups by random number table: namely sham-operated group (sham group), trauma group (TBI group), and …

View Post

Oral rinse with hydrogen-rich is helpful in treating dental diseases

In In vitro studies by CHESS

The accumulation of oral bacterial biofilm is the main etiological factor of oral diseases. Recently, electrolyzed hydrogen-rich water (H-water) has been shown to act as an effective antioxidant by reducing oxidative stress. In addition to this general health benefit, H-water has antibacterial activity for disease-associated oral bacteria. However, little is known about the effect of H-water on oral bacterial biofilm. …

View Post

Hydrogen-rich water achieves cytoprotection from oxidative stress injury in human gingival fibroblasts

In In vitro studies by CHESS

The aim of the present study is to investigate protective effects of hydrogen-rich water (HW) against reactive oxygen species (ROS)-induced cellular harmful events and cell death in human gingival fibroblasts (HGF) and three-dimensional (3D-) gingival tissue equivalents. HW was prepared with a magnesium stick in 600-mL double distilled water (DDW) overnight. Dissolved hydrogen was about 1460 ± 50 μg/L versus approximately 1600 μg/L for …

View Post

Effects of hydrogen rich water on prolonged intermittent exercise

In Exercise, Human studies by CHESS

Recent studies showed a positive effect of Hydrogen Rich Water (HRW) intake on acid-basic homeostasis at rest. The authors investigated 2-weeks of HRW intake on repeated sprint performance and acid-base status during prolonged intermittent cycling exercise. In a cross over single-blind protocol, eight trained male cyclists (age [mean ± SD] 41±7 years, body mass 72.3±4.4 kg, height 1.77±0.04 m, maximal …

View Post

Hydrogen-rich saline for hepatectomy-induced cognitive dysfunction

In Animal studies, Liver, Nervous system by CHESS

This study aims to investigate the protective effects and underlying mechanisms of hydrogen-rich saline on the cognitive functions of elder mice with partial hepatectomy-induced postoperative cognitive dysfunction (POCD). Ninety-six old male Kunming mice were randomly divided into 4 groups (n = 24 each): control group (group C), hydrogen-rich saline group (group H), POCD group (group P), and POCD + hydrogen-rich saline group (group PH). …