Hydrogen in Biomedicine

Water bubbles

Molecular hydrogen might be the next big thing in biomedicine, with over 300 studies published in the past decade suggesting beneficial effects of this novel agent. However, collecting and interpreting unbiased data using evidence-based approach is a must to provide the best guidelines in making decisions about the use of hydrogen in health and disease.

President Signature

Professor Sergej M. Ostojic, MD, PhD

Studies in Numbers

Studies included

Our trials


Our Papers

In 2017, we published several papers about molecular hydrogen in well respected peer-reviewed journals, focused to H2 bioactivity and its use in cardiometabolic disorders.

In this double blind, placebo-controlled trial, we found that hydrogen-generating minerals reduced body fat percentage and arm fat index in middle-aged overweight women; this was accompanied by a significant drop in serum triglycerides and fasting serum insulin after H2 administration.
The study was published in Irish Journal of Medical Science.

It seems that several hydrogenogenic bacteria located outside the gut are also capable to generate H2 via nutrients utilisation. For example, the mouth and pharynx are colonised by resident anaerobes capable for endogenous production of hydrogen via carbohydrate fermentation. Read full paper in Postgraduate Medical Journal.

Several alternative pathways are advanced as main proxies for energy-modulating effects of molecular hydrogen, with this mechanisms could be at least partially responsible for favorable impact of H2 in many neurodegenerative and cardiometabolic diseases. Read free full text in Theranostics.

Donate to Hydrogen Medicine Initiative

There are several ways of supporting our activities, besides reading and spreading evidence-based information from this portal. You can also donate funds that will enable us to continue our research that addreses different aspects of hydrogen application in biomedicine.


Student Spotlight

A preventive and therapeutic medical gas

Since the 2007 discovery that H2 has selective antioxidant properties, multiple studies have shown that H2 has beneficial effects in diverse animal models and human diseases.

Read More from Open Acces 2017 Oncotarget paper →

About Us

This portal is an independent division of the Center for Health, Exercise and Sport Sciences (CHESS) web structure, established to present scientific studies on biomedical use of molecular hydrogen, and to promote institutional research intitatives in hydrogen research. All entries are collected from peer-reviewed academic journals and publications, and pertinent scientific events. Our mission is to collect an unbiased data and provide current best evidence in making decisions about the use of molecular hydrogen in health and disease.


Center for Health, Exercise and Sport Sciences
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